Endocrine Abstracts

Introduction: Kisspeptins and their cognate receptor GPR-54 (Kiss-1) were found to be regulators of the hypothalamo-pituitary–gonadal axis. It is under debate if the onset of central precocious puberty (CPP) could be triggered by early increase of kisspeptin. We aimed to assess serum kisspeptin levels in girls in order to evaluate its potential as a reliable biochemical marker for differential diagnosis of CPP.Materials and methods: The girls enroll...

Background: The prevalence of precocious puberty (PP) and its relationship to optic pathway tumours in patients suffering from neurofibromatosis type 1 (NF1) is significantly greater than in normal population.Objectives: We present a rare case of precocious puberty in neurofibromatosis type 1 which is not associated with optic pathway tumour but with a tuber cinereum hamartoma.Case report: We present the case of a 5-year and 5-mont...

Introduction: The prevalence of obesity in children and adolescents has dramatically increased over the last 20–30 years.Childhood overweight is associated with higher risk of obesity into adulthood and a higher incidence of metabolic consequences.Objectives: To identify the prevalence of metabolic complications in obese children and adolescents.Methods: One thirty-two obese children and adolescents (age...

Introduction: Thyroid cancer in childhood and adolescence represents 1.5–3% of all carcinomas in this group of age. Our purpose is to define clinical and pathological features, therapeutical complications and follow-up characteristics and survival of a group of children and adolescents with thyroid carcinomas.Design: We report a retrospective study of 26 children and adolescents with thyroid carcinoma who were investigated in our institution from Ja...